sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate
CAS: 496807-11-5
Molecular Formula: C24H29NaO5
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate - Names and Identifiers
| Name | sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate |
| Synonyms | Beraprost sodium (Relative stereochemistry) |
| CAS | 496807-11-5 |
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate - Physico-chemical Properties
| Molecular Formula | C24H29NaO5 |
| Molar Mass | 420.47383 |
| In vitro study | Beraprost sodium (0.1, 1.0, and 10.0μM; 24 hours) treatment leads to a significant increase in the number of tube formation, BPS plays an important role on angiogenic activity. Beraprost sodium (0.1, 1.0, and 10.0μM; 24 hours) treatment let VE-cadherin at regions of cell–cell contact becomes more abundant and the morphology of endothelial cells tends to be normal compared with those cultured under hypoxia conditions. |
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate - References
| biological activity | Beraprost sodium is a prostacyclin analog, it is a stable and orally active prodrug of pgi2. Beraprost sodium is an effective vasodilator and has the potential to study pulmonary hypertension by dilating renal vessels and improving microcirculation. |
| Target | prodreg of PGI2; Vasodilator |
| Animal Model: | 6-8-week-old C57Bl/6J Male Mice |
| Dosage: | 0.6mg/kg |
| Administration: | Oral adminstration; 0.6mg/kg; once daily; 3 or 7 days |
| Result: | Mitigated the development of renal interstitial fibrosis. |
Last Update：2024-04-09 20:49:11
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Product Name: Beraprost Impurity 10 Sodium Salt Visit Supplier Webpage Request for quotationCAS: 496807-11-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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